New Invention Profile
| Publication No: | AU2018364807 [Australia] | Application No: | 2018364807 |
| Title: | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | ||
| Publication Date: | 27-04-2020 | File Date: | 27-04-2020 |
| Inventor(s): | Talukdar Arindam, Ganguly Dipyaman, Mukherjee Ayan, Paul Barnali, Rahaman Oindrila, Kundu Biswajit, Roy Swarnali, Deblina Raychaudhuri | ||
| IPC Classification: | A61K 31/52, A61P 37/02, C07D 473/16 | ||
| Abstract: | The present invention provides novel purine based compounds of formula 1, method of preparation of purine based compounds and its composition useful for inhibiting signalling through Toll-like receptors. These compounds are useful in inhibiting immune stimulation involving toll –like receptor 9 (TLR9). These can be used in treatment of autoimmune disease and inflammation where aberrant activation of TLR9 plays role. |
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Industrial Applications
Biotechnology [Biological Science]
Formulations [Drugs and Pharmaceuticals]