Patent Profile
| Patent No: | AU2018364807 [Australia] | Application No: | AU2018364807 |
| Title: | Purine based compounds as toll-like receptor 9 antagonist | ||
| Issue Date: | 19-05-2022 | File Date: | 05-11-2018 |
| Inventor(s): | Talukdar Arindam; Ganguly Dipyaman; Mukherjee Ayan; Paul Barnali; Rahaman Oindrila; Kundu Biswajit; Roy Swarnali; Deblina Raychaudhuri | ||
| IPC Classification: | A61K31/52, A61P37/02, C07D473/16 | ||
| Abstract: | The present invention provides novel purine based compounds of formula 1, method of preparation of purine based compounds and its composition useful for inhibiting signalling through Toll-like receptors. These compounds are useful in inhibiting immune stimulation involving toll-like receptor 9 (TLR9). These can be used in treatment of autoimmune disease and inflammation where aberrant activation of TLR9 plays role. | ||
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