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Patent No: IN558276 [India] Application No: IN202011024499
Title: AN INTEGRATED CONTINUOUS FLOW MACHINE PROCESS SYSTEM FOR THE SYNTHESIS OF DACLATASVIR FREE BASE AND ANALOG THEREOF
Issue Date: 21-01-2025 File Date: 11-06-2020
Inventor(s): Ajay Kumar Singh; Srihari Pabbaraja; Subhash Ghosh; Abhilash Rana
IPC Classification: G01N 35B, A61K 3141
Abstract:
The present invention relates to an integrated continuous flow process for the synthesis of daclatasvir (DCV). More particularly, the  invention relates to a fully automated, multi-operational, continuous flow process which does not require intermediate purification  and solvent exchange steps to obtain antiviral drug daclatasvir free base of general formula I.
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Industrial Applications Synhtesis Procesess [Drugs and Pharmaceuticals]