| Patent No: | US12023365 [USA] | Application No: | US201816753969 |
| Title: | SUSTAINED RELEASE FORMULATIONS OF CROCUS SATIVUS | ||
| Issue Date: | 02-07-2024 | File Date: | 18-10-2018 |
| Inventor(s): | BHARATE SONALI SANDIP, KUMAR VIKAS, SINGH ROHIT, RANI SARITA, GUPTA MEHAK, KUMAR AJAY, BHARATE SANDIP BIBISHAN, VISHWAKARMA RAM | ||
| IPC Classification: | A61K 9/16, A61K 36/88, A61P 25/28 | ||
| Abstract: | The present invention is related to the novel oral dosage form for sustained release of crocin-1, a active constituent of Crocus sativus extract or fraction and a process for preparing the same wherein the extract is wet-granulated using excipients, biodegradable polymers and/or non-biodegradable polymers alone or in combination. The said formulations are useful for the treatment of chronic inflammatory diseases wherein NLRP3 inflammasome is involved. | ||