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Patent No: US12023365 [USA] Application No: US201816753969
Title: SUSTAINED RELEASE FORMULATIONS OF CROCUS SATIVUS
Issue Date: 02-07-2024 File Date: 18-10-2018
Inventor(s): BHARATE SONALI SANDIP, KUMAR VIKAS, SINGH ROHIT, RANI SARITA, GUPTA MEHAK, KUMAR AJAY, BHARATE SANDIP BIBISHAN, VISHWAKARMA RAM
IPC Classification: A61K 9/16, A61K 36/88, A61P 25/28
Abstract: The present invention is related to the novel oral dosage form for sustained release of crocin-1, a active constituent of Crocus sativus extract or fraction and a process for preparing the same wherein the extract is wet-granulated using excipients, biodegradable polymers and/or non-biodegradable polymers alone or in combination. The said formulations are useful for the treatment of chronic inflammatory diseases wherein NLRP3 inflammasome is involved.
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