| Publication No: | EP4025560 [European Patent Office (EPO)] | Application No: | EP20860716 |
| Title: | SOLVENT FREE CONTINUOUS PROCESS FOR THE SYNTHESIS OF METFORMIN HYROCHLORIDE | ||
| Publication Date: | 11-10-2023 | File Date: | 04-09-2020 |
| Inventor(s): | Kulkarni, Amol Arvind; Sharma, Brijesh | ||
| IPC Classification: | C07C 277/08, C07C 279/26 | ||
| Abstract: | The present invention provides a continuous solvent free and additive free process for the synthesis of Metformin Hydrochloride in a screw reactor. >90% conversion of the solid substrates without solvent is obtained in a screw reactor to produce Metformin Hydrochloride with at least 90% selectivity. |
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