Patent Profile
| Patent No: | IN231553 [India] | Application No: | 0274DEL2003 |
| Title: | A process for obtaining para-aescin from indian horse chestnut (aesculus indica) | ||
| Issue Date: | 06-03-2009 | File Date: | 12-03-2003 |
| Inventor(s): | SINGH BIKRAM | ||
| IPC Classification: | A61K 35/78 | ||
| Abstract: | A process for obtaining p-aescin from Indian horse chestnut (Aesculus indica The present invention relates to development of a process for purification of (3-aescin from Indian horse chestnut (Aesculus indica). Aescin was obtained from Indian horse chestnut (Aesculus indica seeds) by drying, grinding and extracting with water and ethyl/methyl alcohol mixture followed by removal of organic solvent and fractionation of aqueous layer with butanol/isopropanol saturated with water. Treating the organic layer i.e. Butanol/isopropanol fraction with base in a separating funnel with gentle shaking. Washing of base treated organic layer with water saturated with butanol followed by passing of organic layer through acidic alumina. Distilling the organic layer to yield aescin as white amorphous powder. The yield is 2.0-3.0% and purity is minimum 90%. | ||
| Licensing Option: | Laboratory scale know-how is available. | ||
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