| Patent No: | IN289560 [India] | Application No: | 0384DEL2009 |
| Title: | Polymeric Nanomatrix Associated Delivery of Kaempferol In Rats To Improve Its Osteogenic Action | ||
| Issue Date: | 14-11-2017 | File Date: | 27-02-2009 |
| Inventor(s): | PRABHAT RANJAN MISHRA, RITU TRIVEDI, GIRISH KUMAR GUPTA, AVINASH KUMAR, VARSHA GUPTA, SRIKANTA KUMAR RATH, KAMINI SRIVASTAVA, NAIBEDYA CHATTOPADHYAY, ANIL KUMAR DWIVEDI | ||
| IPC Classification: | A61K, A61K9/52, A01N43/04, A61K9/50, A61K31/70, B01J13/00, B05D3/00, A61K31/352, A61K31/7048, A61P19/00, A61P19/10, A61K9/16 | ||
| Abstract: | The present invention relates to a microcapsule for controlled release of flavanoid compound and a process for preparation thereof. The microcapsule comprising a core particle consisting of a calcium salt, Pluronic F68 [poly (ethylene oxide-co-polypropylene oxide), block poly oxyethylene-polypropylene block copolymer], loaded with a flavanoid compound, the resulting core particle having a plurality of alternate layers of cationic and anionic polyelectrolytes adsorbed thereon and an outer layer formed by a bile salt, wherein the flavanoid is ranging between 10 to 96 % by weight. | ||