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Patent No: US8496964 [USA] Application No: 13/203603
Title: Controlled release micro-capsule for osteogenic action
Issue Date: 30-07-2013 File Date: 26-08-2011
Inventor(s): Mishra; Prabhat Ranjan (Lucknow, IN), Trivedi; Ritu (Lucknow, IN), Gupta; Girish Kumar (Lucknow, IN), Kumar; Avinash (Lucknow, IN), Gupta; Varsha (Lucknow, IN), Rath; Srikanta Kumar (Lucknow, IN), Srivastava; Kamini (Lucknow, IN), Chattopadhyay; Naibedya (Lucknow, IN), Dwivedi; Anil Kumar (Lucknow, IN)
IPC Classification: A61K 9/52, B05D 3/00, B01J 13/00, A61K 31/70, A61K 9/50, A01N 43/04
Abstract: The present invention relates to a microcapsule for controlled release of flavanoid compound and a process for preparation thereof. The microcapsule comprising a core particle consisting of a calcium salt, Pluronic F68 [poly (ethylene oxide-co-polypropylene oxide), block poly oxyethylene-polypropylene block copolymer], loaded with a flavanoid compound, the resulting core particle having a plurality of alternate layers of cationic and anionic polyelectrolytes adsorbed thereon and an outer layer formed by a bile salt, wherein the flavanoid is ranging between 10 to 96% by weight.
Licensing Option: Laboratory willing to jointly develop technology with industrial partner.
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Industrial Applications Drug delivery [Drugs and Pharmaceuticals] Formulations [Drugs and Pharmaceuticals]