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Publication No: EP4408974 [European Patent Office (EPO)] Application No: EP2022875349
Title: A composition for anti-bacterial bio-cellulosic patches useful for transdermal drug delivery and a process for the preparation thereof
Publication Date: 07-08-2024 File Date: 30-09-2022
Inventor(s): Saran, Saurabh; Kumar, Manoj; Chib, Shifali; Bhat, Rahul; Nandi, Utpal; Dogra, Ashish; Khan, Inshad Ali
IPC Classification: C12N 000120, A61P 003104
Abstract:
The present invention relates to the development of antibacterial biocellulosic patches/membranes for transdermal drug delivery. Novel high cellulose producing bacterial strain Komagataeibacter hansenii (MBS-8) has been isolated. The production and purification process of biocellulosic membranes is developed in such a way that the membranes produced are of desired thickness and length, suitable for drug impregnation in a cost-effective manner for the development of transdermal patches. Further, a process for efficient drug impregnation of Mupirocin in BC membranes has been developed. Weight and drug content of mupirocin impregnated BCM were found to be uniform.
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Industrial Applications Drug delivery [Drugs and Pharmaceuticals] Synhtesis Procesess [Drugs and Pharmaceuticals]