New Invention Profile
| Publication No: | IN202411023678 [India] | Application No: | IN202411023678 |
| Title: | A continuous micro-electro-flow process for preparation of homologated carboxylic acid and alcohol thereof | ||
| Publication Date: | 17-10-2025 | File Date: | 22-03-2024 |
| Inventor(s): | Ajay Kumar Singh; Sanjeev Kumar | ||
| IPC Classification: | B01J23/72, C07C205/06, B01J31/02, B01J19/02, C07D403/14, C25B3/29 | ||
| Abstract: | The present invention discloses an electro-micro-flow induced method for cross-electrophile coupling of activated C(sp3)-O bonds with CO2, enabling the synthesis of aliphatic carboxylic acids. This method involves sequential reactions of sulfonium salts followed by replacement of CO2 with CS2, aldehydes, ketones, or electron- deficient olefins, resulting in the formation of corresponding dithiol acids, deoxygenated Barbier-type products, and 1,4-addition products. The process effectively addresses key challenges in the field of cross-electrophile coupling and organosulfur chemistry by eliminating the need for expensive catalysts, reductants, or oxidants. Additionally, it mitigates issues related to low surface-to-volume ratios in gas-liquid reactions. |
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