New Invention Profile
| Publication No: | IN202311059067 [India] | Application No: | IN202311059067 |
| Title: | A LATERAL FLOW ASSAY DEVICE COMPRISING A COVALENTLY FUNCTIONALIZED GOLD NANOROD CONJUGATE, AND USES THEREOF | ||
| Publication Date: | 07-03-2025 | File Date: | 01-09-2023 |
| Inventor(s): | Sanjana Sudhir Varma; Bhushan Pradosh Chaudhari | ||
| IPC Classification: | G01N 33/543, G01N 33/569, B01J 23/52, B82Y 30/00 | ||
| Abstract: | The present disclosure relates to an analyte detection device for detecting one or more analytes present in test samples. Specifically, the present disclosure relates to covalently-functionalized gold nanorod conjugates and a lateral flow assay device comprising the same for in-vitro detection of TSH levels from biological samples. The present disclosure also relates to the method of producing the lateral flow assay device comprising covalently-functionalized gold nanorod conjugates. |
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| Startup Options: | Advantages and applications of the present disclosure: • Provides modified gold nanorods (GNRs), which are highly stable and sensitive for TSH detection. • TSH antibody-gold nanorods bioconjugate of 20 OD was used to prepare LFA. However, LFA also worked with 5 OD and 10 OD bioconjugates. • The concentration of capture antibody (10-2429) was varied on test line from 1-3 mg/ml at 3mg/ml we got the appropriate results. • The sample volume of 50µl for the LFA was optimized. The volume was varied from 30-50µl. |
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CSIR-National Chemical Laboratory[CSIR-NCL]
: director[at]ncl[dot]res[dot]in
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:http://www.ncl-india.org/
Industrial Applications
Diagnostics [Medical Devices and Diagnostics]
Instrumentation, Appliances, Devices Applications [Instrumentation, Appliances, Devices]
Nanomaterials [Materials]