| Publication No: | IN202311038373 [India] | Application No: | IN202311038373 |
| Title: | A LOW-COST FABRICATION METHOD OF HIGHLY SENSITIVE SURFACE-ENHANCED RAMAN SPECTROSCOPY SUBSTRATE FOR BIOCHEMICAL SENSING | ||
| Publication Date: | 13-12-2024 | File Date: | 02-06-2023 |
| Inventor(s): | RAHUL PRAJESH; RAKESH KUMAR SAINI; THOUTI ESHWAR; ANAND KUMAR UPADHAYAY; PRADEEP KUMAR | ||
| IPC Classification: | G01N 21/65, G01J 3/44, G01N 21/552, G01N 33/553, B82Y 15/00 | ||
| Abstract: | Surface-enhanced Raman spectroscopy (SERS), is a powerful vibrational spectroscopy technique that amplifies electromagnetic fields produced by the triggering of localized surface plasmons to provide highly sensitive structural identification of low-concentration. In order to achieve maximum enhancement, the size, shape, and roughness of the substrate should be optimized. Gold is the most commonly used due to its higher chemical stability and lower toxicity as compared to silver, which is vulnerable to oxidation. In the present work, we fabricated a SERS substrate using a simpler, mass-producible, and low cost approach. The device has an array of 3D structures which provide uniform roughness on the surface. The substrate material is low-cost as well as biodegradable. Here a thin layer of gold is deposited on the substrate to create localized surface plasmon. These surface plasmons enhance the Raman signal by many folds. Test molecule with concentration as low as 10-9 M is successfully detected. The enhancement factor ranging from 104 to 106 was achieved for the test molecules on the developed SERS substrate. |
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