New Invention Profile
| Publication No: | EP4419503 [Europe] | Application No: | EP2022883134 |
| Title: | A method for the preparation of indole-3-carboxylic acid derivatives | ||
| Publication Date: | 19-11-2025 | File Date: | 20-10-2022 |
| Inventor(s): | Deb, Indubhusan; Bhowmik, Arup | ||
| IPC Classification: | C07D 020900, A61K 003146, C07D 045104 | ||
| Abstract: | The present invention provides a new synthetic method for the preparation of building block indole-3-carboxylic acid (ICA) derivatives used as a key starting material to produce several artificial drugs. An efficient, safe, operationally simple, cost-effective method for the preparation of several ICA derivatives has been introduced in a very simple way. Utilizing easily available starting material, reagent, and solvent several key starting materials of ICA derivatives have been synthesized rapidly indicates the novel method is functional group tolerable. The preparation process does not involve use of any reducing agents or transition metals in the economically viable and operationally simple condition in one pot. ICA derivatives have been generated from isatin derivative in one step and this methodology is important with a wide range of applications from the drug development and material synthesis point of view. |
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Industrial Applications
Chemistry, Chemical Processes Polymers [Chemistry, Chemical Processes]
Formulations [Drugs and Pharmaceuticals]
Synhtesis Procesess [Drugs and Pharmaceuticals]