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 Technology Profile

Title:

A Plant Flower Extract as an Anti-peptic Ulcer Pharmaceutical Formulation

Value Proposition:

The present invention provides a process for the isolation of extract or bioactive fractions from plant Woodfordia fruticosa, especially from the flowers and also offers a method of treating a subject for ulcers and related diseases, said method comprises administering an effective amount of a pharmaceutical composition.
A pharmaceutical composition comprising an effective amount of an extract or lyophilized extract or at least one bioactive fraction obtained from the plant Woodfordia fruticosa along with one or more pharmaceutically acceptable additives/carriers for treating ulcer caused by the conditions such as stress induced ulcer, peptic ulcer, cold restraint induced ulcer, drug induced ulcer and acid induced ulcer, also used as specific inhibitor of gastric H+, K+-ATPase and anti-Helicobacter pylori activity.
In conclusion this herbal formulation offers a comprehensive management of human peptic ulcer diseases giving even in some cases quadruple therapy, that too from a single plant part.

Summary Application:

Peptic Ulcer diseases.

A pharmaceutical composition for treating peptic ulcer and related ulcerical conditions, caused by various aetiologies such as those arising from stress induced ulcer, peptic ulcer, cold restraint induced ulcer, drug induced ulcer and acid induced ulcer.

Advantages:

The composition can be in the form of tablets, capsules, syrup or by any other form known in the art and is administered orally, intramuscularly, and by any other conventional methods, given as a single bolus dose or a multiple doses.
Composition may be used for therapeutic as well as prophylactic treatment of peptic ulcer.
Excellent protection against a range of ulcerical conditions arising from diverse causes
In terms of therapeutic management of peptic ulcer diseases, the applicant gets triple therapy and even in some cases quadruple therapy ie: the control of majority of the therapeutic potential of the currently prevailing modem medicines by a single plant part.

Tech. Readiness Level:
CSIR-Indian Institute of Chemical Biology
CSIR-Indian Institute of Chemical Biology[CSIR-IICB]
:  director[at]iicb[dot]res[dot]in
:91-33-24730492
:https://iicb.res.in/
Industrial Applications: Formulations [Drugs and Pharmaceuticals]
Patent(s): IN232610 US7291353