New Invention Profile
| Publication No: | EP4452952 [Europe] | Application No: | EP2022910395 |
| Title: | A preparation of quinazolinediones and use thereof | ||
| Publication Date: | 03-12-2025 | File Date: | 19-12-2022 |
| Inventor(s): | Talukdar Arindam; Chakrabarti Partha; Sarkar Dipayan; Chowdhury Saheli; Goon Sunny; Sen Abhishek; Ghosh Dastidar Uddipta; Patra Binita; Hoque Israful | ||
| IPC Classification: | C07D023996, A61K0031517, A61P000116, C07D040104, C07D040106, C07D040306, C07D040312, C07D048704 | ||
| Abstract: | The present invention described herein relates to a compound having Structure I for treating diseases and disorders for which inhibition or modulation of the Ubiquitin Ligase COP1 enzyme produces a physiologically beneficial response, in particular for the treatment of Non-Alcoholic Fatty Liver Disease (NAFLD). These compounds having Structure I are capable of increasing the level of adipose triglyceride lipase (ATGL). Also provided is the process of preparing compounds having Structure I. |
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