New Invention Profile
| Publication No: | US2025154112 [USA] | Application No: | US18723847 |
| Title: | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | ||
| Publication Date: | 15-05-2025 | File Date: | 19-12-2022 |
| Inventor(s): | Talukdar Arindam; Chakrabarti Partha; Sarkar Dipayan; Chowdhury Saheli Kumar; Goon Sunny; Sen Abhishek; Ghosh Dastidar Uddipta; Patra Binita; Hoque Israful | ||
| IPC Classification: | C07D 239/96, A61K 31/517, A61K 31/5377, C07D 401/04, C07D 401/06, C07D 403/06, C07D 403/12 | ||
| Abstract: | The present invention described herein relates to a compound having Structure I for treating diseases and disorders for which inhibition or modulation of the Ubiquitin Ligase COP1 enzyme produces a physiologically beneficial response, in particular for the treatment of Non-Alcoholic Fatty Liver Disease (NAFLD). These compounds having Structure I are capable of increasing the level of adipose triglyceride lipase (ATGL). Also provided is the process of preparing compounds having Structure I. |
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: director[at]iicb[dot]res[dot]in
:91-33-24730492
:https://iicb.res.in/