| Publication No: | IN202411061598 [India] | Application No: | IN202411061598 |
| Title: | A process for the preparation of bempedoic acid | ||
| Publication Date: | 20-02-2026 | File Date: | 13-08-2024 |
| Inventor(s): | Dumbala Srinivasa Reddy; Remya Ramesh; Chada Raji Reddy; Satya Ravi Teja Miriyala; Adla Vijender; Rahul Choudhury | ||
| IPC Classification: | A61K31/20, C07C51/09, A61P9/00, A61P3/06, C07C59/245 | ||
| Abstract: | The present disclosure relates to a process for the preparation of bempedoic acid or its pharmaceutically acceptable salts. The main strategy involves preparing the keto diacid intermediate through hydrolysis of ketene intermediate to produce bempedoic acid, thereby avoiding the use of the dialkylation of p-toluenesulfonyl methyl isocyanide (TosMIC) reagent. The present disclosure also provided intermediates for the preparation of bempedoic acid. |
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