| Publication No: | IN202311073665 [India] | Application No: | IN202311073665 |
| Title: | A PROCESS FOR THE PREPARATION OF GLIFLOZIN AGLYCONES | ||
| Publication Date: | 02-05-2025 | File Date: | 27-10-2023 |
| Inventor(s): | Chada Raji Reddy; Chennam Ramu; Subhash Ghosh; Gangarajula Sudhakar; Kumaraguru Thenkrishnan; Avula Shivakrishna | ||
| IPC Classification: | C07H 7/04, A61K 31/7034, A61P 3/10, C07H 15/04, C07H 1/00, C07D 309/10 | ||
| Abstract: | The present invention relates to a novel process for the preparation of gliflozin aglycone through a telescopic approach using ortho-lithiation of 1,4-dihalobenzene followed by reacting with corresponding aromatic or heteroaromatic aldehydes and reduction of the resulted in diarylmethanol or (aryl)(heteroaryl)methanol intermediate as key steps. |
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