| Publication No: | WO2025088634 [PCT] | Application No: | IN2024/052131 |
| Title: | A PROCESS FOR THE PREPARATION OF GLIFLOZIN AGLYCONES | ||
| Publication Date: | 01-05-2025 | File Date: | 25-10-2024 |
| Inventor(s): | Sudhakar Gangarajula; Ramu Chennam; Ghosh Subhash; Reddy Chada Raji; Thenkrishnan Kumaraguru; Shivakrishna Avula | ||
| IPC Classification: | C07C 15/16, C07C 25/18, C07D 307/04, C07D 333/54 | ||
| Abstract: | The present invention relates to a novel process for the preparation of gliflozin aglycone through a telescopic approach using ortho-lithiation of 1,4-dihalobenzene followed by reacting with corresponding aromatic or heteroaromatic aldehydes and reduction of the resulted in diarylmethanol or (aryl)(heteroaryl)methanol intermediate as key steps. |
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