New Invention Profile
| Publication No: | US20260242377 [USA] | Application No: | US18724883 |
| Title: | A process for the preparation of ledipasvir | ||
| Publication Date: | 20-08-2026 | File Date: | 24-11-2023 |
| Inventor(s): | Gangarajula Sudhakar; Chennam Ramu; Kumaraguru Thenkrishnan; Baburao Rode Haridas; Maddi Reddy Sridhar; Chada Reddy Raji; Ghosh Subhash | ||
| IPC Classification: | C07D471/08, C07D207/22, C07D403/12, C07F5/02 | ||
| Abstract: | The present disclosure relates to process for the preparation of Ledipasvir (I) or of its pharmaceutically acceptable salts. The present disclosure also provides novel intermediates (IV-XI) that are used in the synthesis of Ledipasvir. The main strategies of the present invention are late-stage functionalization such as difluorination and cyclopropanation of the key intermediates of Ledipasvir (I). |
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