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Publication No: US2024239832 [USA] Application No: US202218558928
Title: A process for the preparation of N4-hydroxycytidine and its derivatives
Publication Date: 18-07-2024 File Date: 03-11-2023
Inventor(s): Mukherjee Debaraj; Ahmed Qazi Naveed; Ahmed Ajaz; Banday Junaid Shafi
IPC Classification: C07H 19/067
Abstract:
This invention provides a process for the preparation of orthogonally protected ribose derivative. Which are further used as donor for the synthesis of N4-hydroxy cytidine and its derivatives by using commercially available materials under very mild reaction condition and short period of time. Thereafter N-hydroxylation of cytidine can be achieved in a short period of time. The intermediates or the final compounds thus obtained can be used for the treatment of viral infections.

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Industrial Applications Chemistry, Chemical Processes Polymers [Chemistry, Chemical Processes] Synhtesis Procesess [Drugs and Pharmaceuticals]