| Publication No: | IN202211028466 [India] | Application No: | 202211028466 |
| Title: | A process for the synthesis of a polymer-ceramic/bioactive glass composite material with biodegradable and antimicrobial properties | ||
| Publication Date: | 22-12-2023 | File Date: | 17-05-2022 |
| Inventor(s): | Majumder, Mousumi; Chakraborty, Jui; Samanta, Swati; Narjinary, Mousumi Baral; Banerjee, Arpita; Roy, Payal; Saha, Rupam | ||
| IPC Classification: | A61, C08, C03, A01 | ||
| Abstract: | The present invention discloses a process for the synthesis of a polymer-nanoceramic/bioactive glass/curcumin based composite material that can be electrospun to form nonwoven films. The base polymer used is PCL, a semicrystalline aliphatic polyester. Several nanofillers such as zinc oxide, titanium dioxide, cobalt-doped bioactive glass, curcumin, etc. have been incorporated in the polymer matrix. Co-doped BG has been prepared by a low-temperature sol-gel method. Precursor solvents have been varied using several binary combinations to improve the porosity of the nonwoven films. The electrospinning parameters have been optimized to produce uniform, bead-free fibre morphology. The spun composite films have shown excellent mechanical properties, superior environmental biodegradability and cytocompatibility. The films have also manifested adequate antimicrobial efficacy against bacterial strain of S. aureus and fungal strain of C. albicans. These films are thus expected to find several applications as medical textiles, eg. in sanitary napkins, diapers, disposable sheets and single-use medical garments, etc. | ||