Technology Profile
| Title: | A Small Molecule Inhibitor of Amyloid Biogenesis |
| Value Proposition: | Novel small molecules which can inhibit α-Synuclein amyloid aggregation, offering a novel therapeutic strategy for treating Dementia with Lewy Bodies (DLB) including Parkinson’s disease (PD). |
| Summary Application: | New molecules/ compositions for Neurodegenerative disease therapeutics |
| Advantages: | No current marketed drugs offer cure for DLB/PD directly, they only alleviate some or other of the symptoms associated with these dementias. Our small molecule demonstrate visible reduction in amyloid formation in cells with no visible cellular toxicity, and offer novel therapeutic strategy for treating these diseases. |
| Tech. Readiness Level: |
CSIR-Centre for Cellular and Molecular Biology[CSIR-CCMB]
: director[at]ccmb[dot]res[dot]in
:91-40-27160222-31, 91-40-27160232-41
:https://www.ccmb.res.in
: director[at]ccmb[dot]res[dot]in
:91-40-27160222-31, 91-40-27160232-41
:https://www.ccmb.res.in
Industrial Applications:
Biological Science Processes/Methods [Biological Science]
Biomolecules [Biological Science]
Biotechnology [Biological Science]
Patent Application(s):
IN202611016426 (Filed)