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 Technology Profile

Title:

Antibacterial Hemostatic Dressing- Stop Bleeding and Prevent Bacterial Infection

Value Proposition:

Hemostatic Wound Dressing market was USD 415 million in 2022, and expected reach up to USD 740 million by 2030. Growing demand for emergency medical care, the indigenously developed patented nanocomposite hemostatic dressing has substantial opportunity for market penetration.

● Hemostatic product is designed for rapid bleeding arrest, prevents bacterial infection and reduce the cytotoxicity and immunogenic response.

● Features: High fluid absorption capacity, Faster clotting efficiency, High mechanical strength, Exhibit broad-spectrum antibacterial properties, Non-irritant and compatibility with the body’s natural process, minimizing adverse reactions.

● Mechanism: Large fluid uptake capacity and adhesion of RBCs due to charge-based interaction.

 

Summary Application:
  • Compression and vasoconstriction
  • Charge based interaction
  • Plasma absorption
  • Platelet aggregation and activation
  • Clotting cascade amplification

The underlying mechanisms of rapid hemostatic properties include

  • compressioncharge based interaction with red blood cells
  • activation of platelets, amplification of the intrinsic and extrinsiccoagulation cascade, and fibrin clot formation
  • Chitosan and graphene nanocomposite material contribute synergistically toaccelerate the blood clotting at the bleeding surface.
Advantages:

Advantages include:

Bleeding control in:-

  • Lacerations
  • Punctures
  • Abrasions
  • Surgical wounds (operative, postoperative, dermatological)
  • Traumatic injuries
Tech. Readiness Level:
CSIR-Indian Institute of Chemical Biology
CSIR-Indian Institute of Chemical Biology[CSIR-IICB]
:  director[at]iicb[dot]res[dot]in
:91-33-24730492
:https://iicb.res.in/
Industrial Applications: Diagnostics [Medical Devices and Diagnostics] Nanomaterials [Materials] Personal care [Drugs and Pharmaceuticals]
Patent(s): IN346127
Patent Application(s): IN201711044089
Photograph(s)