| Publication No: | IN202311006157 [India] | Application No: | 202311006157 |
| Title: | Aptamer based detection of SARS-CoV-2 infection | ||
| Publication Date: | 02-08-2024 | File Date: | 31-01-2023 |
| Inventor(s): | Amogh Milind Auti; Yogesh Laxmirajam Bhandari; Sanjana Sudhir Varma; Bhushan Pradosh Chaudhari; Koteswara Rao Vamkudoth | ||
| IPC Classification: | C07K 16/10, C12N 15/13 | ||
| Abstract: | The present invention relates to development of novel ssDNA aptamers comprising the oligonucleotide sequence that detect receptor-binding domain (RBD) of Severe Acute Respiratory Syndrome Corona virus (SARS-nCoV-2) infection. The ssDNA aptamers of the present invention may be used in lateral flow assays, electrochemical sensors and calorimetric sensors using gold nanoparticles. The present invention also relates to an analytical composition comprising said ssDNA aptamers. Further, the present invention also relates to a diagnostic kit for detecting RBD of SARS-nCoV-2. |
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