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Publication No: IN202411032697 [India] Application No: IN202411032697
Title: Chimeric Antigen Receptor (CAR) molecule for cancer therapy
Publication Date: 28-11-2025 File Date: 24-04-2024
Inventor(s): Ramalingam Sivaprakash; Iyer Aditya; Nafiz Mehwish; Gupta Pragya; Saravanakumar Vinodh
IPC Classification: C07K16/28, A61K35/17, A61P35/00, C07K14/725, A61K39/00
Abstract:
The present invention relates to a Chimeric Antigen Receptor (CAR) molecule for cancer therapy. The present invention more particularly relates to a multi-antigen  targeting CAR molecule comprising antigen-binding domain;a hinge region;a transmembrane domain (TM);co-stimulatory domain; and an intracellular signalling  domain. These CAR molecules provides significant benefits to patients by addressing clinical challenges such as tumor heterogeneity, tumour antigen loss or escape and  ensuring enhanced persistence of the CAR-T cells.
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Industrial Applications Biotechnology [Biological Science] Formulations [Drugs and Pharmaceuticals]