| Publication No: | IN202411032697 [India] | Application No: | IN202411032697 |
| Title: | Chimeric Antigen Receptor (CAR) molecule for cancer therapy | ||
| Publication Date: | 28-11-2025 | File Date: | 24-04-2024 |
| Inventor(s): | Ramalingam Sivaprakash; Iyer Aditya; Nafiz Mehwish; Gupta Pragya; Saravanakumar Vinodh | ||
| IPC Classification: | C07K16/28, A61K35/17, A61P35/00, C07K14/725, A61K39/00 | ||
| Abstract: | The present invention relates to a Chimeric Antigen Receptor (CAR) molecule for cancer therapy. The present invention more particularly relates to a multi-antigen targeting CAR molecule comprising antigen-binding domain;a hinge region;a transmembrane domain (TM);co-stimulatory domain; and an intracellular signalling domain. These CAR molecules provides significant benefits to patients by addressing clinical challenges such as tumor heterogeneity, tumour antigen loss or escape and ensuring enhanced persistence of the CAR-T cells. |
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