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Publication No: IN202411032696 [India] Application No: IN202411032696
Title: Composite scaffold for cartilage regeneration and its process thereof
Publication Date: 28-11-2025 File Date: 24-04-2024
Inventor(s): Bodhak Subhadip; Balasubramanian Rathina Vel; Pal Aniruddha; Balla Vamsi Krishna; Rahaman Shaikh Hasanur
IPC Classification: A61P19/00, A61P19/02, A61K38/18, A61L27/56, A61F2/30
Abstract:
The present invention relates to composite scaffold for cartilage regeneration and its process thereof. The composition of composite scaffold is comprised of 7.5-15wt%  PGS, 7.5-15wt% PCL, 6-8wt% of protein/growth factor loaded SGNP, and 50-100µg of protein (BSA)/growth factor (GDF-5) offering excellent protein encapsulation  efficiency into fibrous matrix, excellent protection of structural and functional properties of encapsulated proteins against process related stresses and capable of  delivering proteins in a sustained therapeutic dosing manner for a prolonged period of time.
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