| Publication No: | US2024116863 [USA] | Application No: | US17932386 |
| Title: | Diphenyl thiourea and diphenyl urea derivatives as inhibitors of endocytosis | ||
| Publication Date: | 11-04-2024 | File Date: | 15-09-2022 |
| Inventor(s): | Kumar Nirmal; Banerjee Indranil; Taily Irshad Maajid; Banerjee Prabal; Singh Charandeep; Sharma Anshul; Ringe Rajesh P; Thakur Krishan Gopal; Singh Priyanka | ||
| IPC Classification: | C07C335/12, C07C275/30 | ||
| Abstract: | The present invention relates to method of inhibition of cellular endocytosis by treating the cells with compound of formula-1 Diphenylthio urea and Diphenylurea derivatives. Said invention also discloses method of treatment of infectious diseases, neurological disease, cancer, kidney disease in a subject in need thereof by administering therapeutically effective concentration of compounds of Formula-1, Diphenylthio urea and Diphenylurea derivatives which are effective inhibitors of cellular endocytosis. Said invention also discloses compounds of Formula-1, Diphenylthio urea and Diphenylurea derivatives and pharmaceutical composition comprising compounds of Formula-1, Diphenylthio urea and Diphenylurea derivatives along with suitable excipients. | ||