New Invention Profile
| Publication No: | IN202211048496 [India] | Application No: | 202211048496 |
| Title: | Electrodeposited sensor for dengue variant detection and method thereof | ||
| Publication Date: | 01-03-2024 | File Date: | 25-08-2022 |
| Inventor(s): | Murugan Veerapandian; Mani Jayakumar; Pandiyaraj Kanagavalli; Chrysantthus Andrew | ||
| IPC Classification: | G01N27/30, G01N27/48, B61B1/02, G01N27/327, G01N33/543 | ||
| Abstract: | The present invention relates to the graphene-based label-free in-situ redox-active electrochemical genosensor platform for ultrasensitive and selective detection/discrimination of dengue serotypes on electrode/SPEs. Electrochemically reduced graphene oxide- tris(bipyridine)ruthenium(II) (ErGO-TBR) nanocomposite was deposited on glassy carbon electrode/SPE substrate via constant potential electrodeposition and comprehensively studied for understanding their physico-chemical properties. Customized probe DNA oligomers immobilized on the as-fabricated ErGO-TBR/SPEs exert selective detection of different DENV variants even at femtomolar level concentrations with high specificity or no cross-reactivity at physiological condition. Empirical results reported in the invention discloses a simple, direct, indicator-free inexpensive genosensor platform on screen printed electrodes for deployment in the point-of- need (resource-limited settings) dengue detection, serotyping and quantification. | ||
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