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Publication No: IN202411016690 [India] Application No: IN202411016690
Title: Gold nanoformulation for cancer therapy
Publication Date: 19-09-2025 File Date: 07-03-2024
Inventor(s): Julappagari, Mamatha; Haque, Shagufta; Tripathy, Sanchita; Londhe, Swapnali; Banerjee, Rajkumar; Patra, Chitta Ranjan
IPC Classification: A61K0033242, A61K004748, A61K004900, A61K005112
Abstract:
The present invention relates to a gold based targeted nanoformulation useful for treating triple negative breast cancer the process of preparation of gold nanoparticle based targeted drug delivery systems (Au-Dex-MUA-Rapa, Au-Dex-MUA-Ola) by the combination of gold nanoparticles as delivery vehicle, dexamethasone as aglucocorticoid receptortargeting ligand, MUA as surfacestabilizing agent and commercially available anti-cancer targeted drug for mTOR (Rapa:rapamycin, everolimus)or PARP(Ola: olaparib) pathway inhibitor for synergistic anti-cancer efficacy.
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