New Invention Profile
| Publication No: | IN202311028952 [India] | Application No: | IN202311028952 |
| Title: | Handheld sensor system for non-invasive detection of neurotransmitters and the method of fabricating sensing element thereof | ||
| Publication Date: | 15-11-2024 | File Date: | 20-04-2023 |
| Inventor(s): | Somenath Roy; Ankita Dutta Chowdhury | ||
| IPC Classification: | G01N 27/327, A61B 5/00, A61B 5/145, G01N 21/552, G01N 27/30 | ||
| Abstract: | A handheld neurotransmitter sensor system for non-invasive detection of target analytes in body fluids comprises disposable sensing element (1), ultra-compact electronic detector (2), OTG cable/connector (3), bio-sensing application software (5) preloaded in the users smartphone (4) or tablet. The method for fabricating a disposable sensor element, in which the active sensing area is made of specific catalytic nanoparticles on a two-dimensional conducting support, a single atomic layer or a few layers, which includes to graphene, reduced graphene oxide and graphitic carbon nitride. The custom functionalized electrode(s), electrically biased through instructions given via a user-friendly mobile application, get(s) energized and cause(s) chemical-to-electrical signal transduction, which is recorded by the handheld sensor system upon amplification and noise filtering. The sensor system in the present invention is capable of detecting neurotransmitters and their metabolites in the concentration range 1nM-1mM. |
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| Startup Options: | The main advantages of the present invention are: • The sensor system comprises a disposable element, which the user can deploy in a plug-and-play mode. The active zones of the sensor element chips are functionalized with specially formulated nano-composites that can selectively detect target analytes, say, a specific or a group of neurotransmitters. • The sensor elements are characterized by high sensitivity, selectivity, fast response, and wide detection range. Target-specific selectivity is the USP of the sensor elements. • The said electronic module does not need a cell, battery, or AC main line power source to be operational. Instead, the module is energized from the user’s smartphone or tablet via a low-cost USB-OTG connector. • It's user-friendly, powered by custom-designed application software with enhanced graphic user interface (GUI) features. The application software displays real-time analysis data and the bio-reference value of the analyte concentration, indexed to age and gender, from the login profile data. • The sensor system can find applications, particularly in the early detection of pheochromocytoma, a rare adrenal medulla tumor, from a urine sample drop. • The invention may used for detection of microbial infections from human body fluids, detection of heavy metals and pathogenic bacteria in drinking water, quality assurance in pharmaceutical industries, point-of-analysis of forensic samples and so on. |
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CSIR-Central Glass and Ceramic Research Institute[CSIR-CGCRI]
: director[at]cgcri[dot]res[dot]in
:91-33- 24735829
:https://www.cgcri.res.in
: director[at]cgcri[dot]res[dot]in
:91-33- 24735829
:https://www.cgcri.res.in
Industrial Applications
Chemistry, Chemical Processes Polymers [Chemistry, Chemical Processes]
Diagnostics [Medical Devices and Diagnostics]
Nanomaterials [Materials]
Sensors [Electronics]