CSIR Technology Portal
CSIR Technology Portal

 Technology Profile

Title:

Hydroxy Propyl Methyl Cellulose (HPMC)

Value Proposition:
  • Control of degree of substitution for both hydroxypropylation and methoxylation governs the characteristics of HPMC.
  • Process involves alkalization, etherification, neutralization and viscosity adjustment.
Summary Application:
  • Double derivative of cellulose with hydroxypropyl groups and methoxyl groups.
  • semisynthetic, inert, viscoelastic polymer used as eye drops, as well as an excipient and controlled-delivery component in oral medicaments
  • emulsifier, thickening and suspending agent, and an alternative to animal gelatin.
  • prepared from cellulose as a starting material
  • pharmaceutical grade developed upto a scale of 1 kg / batch.
Advantages:
  • Artificial tears
  • Tablet coating to replace gelatin
  • Thickening agent & film former
  • Hydrophilic matrix
Tech. Readiness Level:
CSIR-Indian Institute of Chemical Technology
CSIR-Indian Institute of Chemical Technology[CSIR-IICT]
:  director[at]iict[dot]res[dot]in
:91-40-27193030
:https://www.iict.res.in
Industrial Applications: Bulk Chemicals [Chemistry, Chemical Processes] Drug delivery [Drugs and Pharmaceuticals] Formulations [Drugs and Pharmaceuticals]