| Publication No: | IN202411001291 [India] | Application No: | IN202411001291 |
| Title: | Improved process for amino alcohol synthesis starting with hydroxyacetone | ||
| Publication Date: | 11-07-2025 | File Date: | 05-01-2024 |
| Inventor(s): | Mali Nilesh Atmaram; Salunkhe Rahul Ravindra; Shivdasani Meesha Jayant | ||
| IPC Classification: | C07D333/34, C07C221/00, C07C225/06, C07C225/16, C07C231/02, C07C233/76 | ||
| Abstract: | The present disclosure relates to a process of preparation of 2-amino alcohol of formula I comprising: i) reacting 2-hydroxyketone or 2-hydroxyaldehyde of formula II in presence of an aminating agent and a solvent under condition to obtain imine intermediate; and ii) processing by hydrogenation the imine intermediate in presence of a metal catalyst and H2 under condition to obtain 2-amino alcohol of Formula I |
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