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Publication No: IN202411001291 [India] Application No: IN202411001291
Title: Improved process for amino alcohol synthesis starting with hydroxyacetone
Publication Date: 11-07-2025 File Date: 05-01-2024
Inventor(s): Mali Nilesh Atmaram; Salunkhe Rahul Ravindra; Shivdasani Meesha Jayant
IPC Classification: C07D333/34, C07C221/00, C07C225/06, C07C225/16, C07C231/02, C07C233/76
Abstract:
The present disclosure relates to a process of preparation of 2-amino alcohol of formula I comprising: i) reacting 2-hydroxyketone or 2-hydroxyaldehyde of formula II in presence of an aminating agent and a solvent under condition to obtain imine intermediate; and ii) processing by hydrogenation the imine intermediate in presence of a metal catalyst and H2 under condition to obtain 2-amino alcohol of Formula I
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Industrial Applications Chemistry, Chemical Processes Polymers [Chemistry, Chemical Processes]