Indole-based Fluorescence Probe for Cell Organelle-Lipid Droplets (LDs)

Indole based fluorescence probe enables the following features to monitor LD in live cell: High Selectivity ,Cell membrane permeability in Live and fixed condition , High S/N ratio , Low Florescence cross talk

Newly designed fluorescence probe of staining live cells for bio-imaging, including novel fluorescent cell labelling dye for Lipid droplet imaging and analysis in real-time/Live samples.Optimal for capturing Live cell Lipid droplet status in wash-free conditions both in vitro and in vivo.The developed probe is easy to synthesize, which lowers the cost of available dyes in the market to stain lipid droplets.In order to monitor the Lipid droplets in Live/ Fixed cells in various cancer/non-cancer cells, and deep tissues via confocal imaging the LipiK510 can be widely used.Hospital, laboratories, the pharmaceutical industry and medical research, vaccine and drug development and disease diagnosis, flow cytometry uses dyes to detect or measure the characteristics of cells or tissues.

Indole based fluorescence probe enables the following features- to monitor LD in live cell: High Selectivity, Cell membrane permeability in Live and fixed condition , High S/N ratio ,Low Florescence cross talk

There are few fluorescence dye probes available for LDs: BODIPY 493/503 and Nile red are the most widely used commercial probes for LDs fluorescence imaging, but their imaging performance is often unsatisfactory due to the small Stokes shift and poor specificity, respectively.