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Publication No: IN202411023758 [India] Application No: IN202411023758
Title: Indole based small molecule antivirals against SARS-COV-2
Publication Date: 31-10-2025 File Date: 26-03-2024
Inventor(s): Arindam Talukdar; Israful Hoque; Binita Patra; Nirmal Das; Krishan Gopal Thakur ; Rajesh Ringe ; Nittu Singh; Akshay Joshi; Ravneet Singh Chawla
IPC Classification: A61P31/14, A61K45/06, A61P31/12, A61P3/00, A61P31/18
Abstract:
The present invention relates to the preparation of indole-based compounds in free form or an acceptable salt form potential therapeutic target as an antiviral agent  against SARS-Cov2. The indole-based small molecules are, capable of antiviral activity in RT-qPCR and cell-based assay in SARS-CoV-2 infected VERO E6 cells, that  may ultimately be used to achieve improved human health in patients against covid-19 or other similar viral diseases.
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