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Publication No: IN202311070421 [India] Application No: IN202311070421
Title: NOVEL BOROSILICATE BASED BIOACTIVE GLASS FOR COATING ON TI-6AL-4V IMPLANTS AND ITS PROCESS THEREOF
Publication Date: 18-04-2025 File Date: 16-10-2023
Inventor(s): Chakraborty; Biswas Kaushik; Bodhak Subhadip
IPC Classification: A61K 9/14, A61K 9/00, A61K 33/08, A61K 33/42, A61P 43/00, B05D 3/02, C23C 4/04, C25D 13/02
Abstract:
While the Ti-6Al-4V alloy is widely preferred for orthopaedic implants, it is crucial to address the potential risks of genotoxicity and implant loosening caused by  released metal ions and the absence of osseointegration, respectively. In this context, the present invention describes novel borosilicate based bioactive glass  compositions, suitable for coating application on Ti-6Al-4V implants. The assessed characteristics of these glasses demonstrate high thermal stability (145?C), fast in  vitro bioactivity(24-72h) and similar linear thermal expansion coefficient (8.5-12.19? 10-6/?C) to that of the alloy. The favorable combination of properties enables  achievement of a well adherent and amorphous coating on the alloy surface, ensuring osseointegration capability and protection against the risk of genotoxicity.  Additionally, this invention presents a commercially viable coating technique that involves cold-spraying followed by thermal treatment, resulting in desired amorphous  coating on the implant surface. Overall, this invention is anticipated to greatly enhance the performance of Ti-6Al-4V based orthopaedic implants.
CSIR-Central Glass and Ceramic Research Institute
CSIR-Central Glass and Ceramic Research Institute[CSIR-CGCRI]
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Industrial Applications Chemistry, Chemical Processes Polymers [Chemistry, Chemical Processes] Coatings [Metallurgy] Glass [Materials] Implants [Medical Devices and Diagnostics]