Preparation and Applications of Non-hazardous Brominating Reagent

A process of preparing a non-hazardous brominating reagent from an aqueous alkaline bromine byproduct solution obtained from bromine recovery plant.

CSIR-CSMCRI has developed a green brominating reagent - a better alternative to the hazardous liquid bromine. This green brominating agent is an attractive source of bromine for bromination of various organic substrates. The reagent has been designed for three main functionalities 1) Brominating Reagent for Substitution (BR-S); 2) Brominating Reagent for Addition Reactions (BR-A); and 3) Brominating Reagent for Oxidations (BR-O). The reagent can be prepared cost-effectively from the intermediate of bromine recovery plants.

• The hazardous liquid bromine could be eliminated altogether.
• The process is environmentally benign
• Brominating reagent is easy to handle.
• No catalyst is required
• The bromine atom efficiency for the aromatic substitution reaction studied is as high as 95-100%