New Invention Profile
| Publication No: | CN118451062 [China] | Application No: | CN202280085647 |
| Title: | Preparation of quinazolinedione and use thereof | ||
| Publication Date: | 06-08-2024 | File Date: | 19-12-2022 |
| Inventor(s): | Talukdar, Arindam; Chakrabarti, Partha; Sarkar, Dipayan; Chowdhury, Saheli; Goon, Sunny; Sen, Abhishek; Ghosh Dastidar, Uddipta; Patra, Binita; Hoque, Israfu | ||
| IPC Classification: | C07D 023996, C07D 040106, C07D 048704 | ||
| Abstract: | The invention as described herein relates to compounds having the structure I for the treatment of diseases and disorders that produce a physiologically beneficial response against the inhibition or modulation of ubiquitin ligase COP1 enzyme, in particular for the treatment of non-alcoholic fatty liver disease (NAFLD). These compounds with structure I can improve the level of fatty triglyceride lipase (ATGL). Also provided are processes for the preparation of compounds having the structure I. |
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Industrial Applications
Chemistry, Chemical Processes Polymers [Chemistry, Chemical Processes]
Formulations [Drugs and Pharmaceuticals]
Synhtesis Procesess [Drugs and Pharmaceuticals]