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Publication No: EP4555002 [European Patent Office (EPO)] Application No: EP23839190
Title: PROCESS FOR SOLVENT FREE CONTINUOUS SYNTHESIS OF AMIDES AND PEPTIDES
Publication Date: 21-05-2025 File Date: 12-07-2023
Inventor(s): Kulkarni Amol Arvindrao; Atapalkar Ranjit Shabu
IPC Classification: C08G 69/04, B01J 19/20, C07C 231/02
Abstract:
The present invention relates to a novel process for the solvent free continuous synthesis of amides and peptides. More particularly, the invention relates to a process for synthesizing amides and peptides using coupling reagents where the process is done at room temperature with lower residence time and solvent free synthesis, producing enhanced yields and purity products.

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