| Publication No: | IN202411043735 [India] | Application No: | IN202411043735 |
| Title: | Pyrano[2,3-c]pyrazole-pyrazolone compounds and a process for preparation thereof | ||
| Publication Date: | 19-12-2025 | File Date: | 05-06-2024 |
| Inventor(s): | Srihari Pabbaraja; Goverdhan Mehta; Alagesan Balasubramani; Sumana Chakravarty; Sudarshana Kokkodu Anantha Bhatta; Roli Kushwaha | ||
| IPC Classification: | C07D401/14, A61K31/415, A61K31/4439, A61K31/473, A61P25/28, C07D487/04, A61K31/519, A61P35/00 | ||
| Abstract: | The present invention relates to a hybrid pyrano[2,3-c]pyrazole-pyrazolones and analogous compounds of formula 3; and a process for the preparation thereof. The invention further relates to identification of bioactivities of synthesized novel hybrid pyrano[2,3-c]pyrazole-pyrazolones. The novel hybrid pyrano[2,3-c]pyrazole- pyrazolones of Formula 3 displayed useful neuroprotective property and inhibited acetylcholine esterase enzyme at the lowest concentration. These compounds were also found to cross the Blood-Brain Barrier. |
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