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Publication No: IN202411043735 [India] Application No: IN202411043735
Title: Pyrano[2,3-c]pyrazole-pyrazolone compounds and a process for preparation thereof
Publication Date: 19-12-2025 File Date: 05-06-2024
Inventor(s): Srihari Pabbaraja; Goverdhan Mehta; Alagesan Balasubramani; Sumana Chakravarty; Sudarshana Kokkodu Anantha Bhatta; Roli Kushwaha
IPC Classification: C07D401/14, A61K31/415, A61K31/4439, A61K31/473, A61P25/28, C07D487/04, A61K31/519, A61P35/00
Abstract:
The present invention relates to a hybrid pyrano[2,3-c]pyrazole-pyrazolones and analogous compounds of formula 3; and a process for the preparation thereof. The  invention further relates to identification of bioactivities of synthesized novel hybrid pyrano[2,3-c]pyrazole-pyrazolones. The novel hybrid pyrano[2,3-c]pyrazole- pyrazolones of Formula 3 displayed useful neuroprotective property and inhibited acetylcholine esterase enzyme at the lowest concentration. These compounds were  also found to cross the Blood-Brain Barrier.
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