New Invention Profile
| Publication No: | IN202211030140 [India] | Application No: | 202211030140 |
| Title: | Recombinant protein for management of sars-cov-2 infection | ||
| Publication Date: | 29-12-2023 | File Date: | 25-05-2022 |
| Inventor(s): | Jitender; Ravi Pratap Narayan Mishra; Reetesh Kumar; Bhusarapu Vikram Kumar; Sneha Singh | ||
| IPC Classification: | A61K39/00, C07K14/005, A61K39/12, A61K39/155, C12N15/50 | ||
| Abstract: | The invention provides a recombinant protein for management of Sars-CoV-2 infection. This invention discloses the SARS CoV-2 Prefusion Stabilized Spike Protein Ectodomain (PSSPE) designs, their codon-optimized polynucleotide sequences, polypeptide sequences, and the use of anengineered expression vector for expression and, use of purified recombinant PSSPE for management of SARS CoV-2. The PSSPE can be used as immunogen/vaccine to generate a robust immune response against SARS-CoV2 in the subjects, as therapeutics and as diagnostic aids. Furthermore, the designed constructs can also be used for development of nucleic acid and viral vector-based vaccines and therapeutics and for the diagnosis of SARS-CoV-2. | ||
CSIR-Institute of Microbial Technology[CSIR-IMTECH]
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: director[at]imtech[dot]res[dot]in
:91-172-2690550
:https://www.imtech.res.in
Industrial Applications
Biomolecules [Biological Science]
Biotechnology [Biological Science]