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Publication No: IN202311057433 [India] Application No: 202311057433
Title: Ring annulated analogue of 14-deoxy-11,12 didehydroandrographolide (14-dda) as anti-cancer agents and process for preparation
Publication Date: 28-02-2025 File Date: 25-08-2023
Inventor(s): Gulshan Kumar; Ravi Shankar; Misbah Tabassum; Zabeer Ahmed; Sanket Kumar Shukla; Bhupesh Kumar Sharma
IPC Classification: C07D 407/04, A61K 31/365, A61P 31/12, A61P 35/00, A61K 31/341, A61K 45/06, C07D 307/33
Abstract:
The present invention discloses analogues of 14-deoxy-11,12-didehydroandrographolide ( 14-DDA) having the formula A, where substituted spiro- isoxazolines ring formed to the exocyclic C8-17 double bond. The present invention also discloses their method of preparation and their use as anti-cancer agents.
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