New Invention Profile
| Publication No: | WO2026053230 [PCT] | Application No: | PCT/IN2025/050742 |
| Title: | Silicon-incorporated HDAC-6 inhibitor for liver and lung fibrotic disorder | ||
| Publication Date: | 12-03-2026 | File Date: | 13-05-2025 |
| Inventor(s): | Reddy, Dumbala Srinivasa; Andugulapati, Sai Balaji; Nandawadekar, Laxman Devappa; Eagala, Ramesh; Sharma, Nidhi; Routholla, Ganesh; Sripadi, Hari Priya | ||
| IPC Classification: | C07D020904, A61P001100, C07D020956, C07D051900, C07D052100, C07F000708 | ||
| Abstract: | The present invention discloses silicon-incorporated HDAC-6 inhibitors of formula (I) and the process of preparation thereof. The invention further relates to methods of treating a group consisting of idiopathic pulmonary fibrosis, hepatic fibrosis, and other fibrotic disorders such as cardiac, kidney, and skin fibrosis. |
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