| Publication No: | US2024041772 [USA] | Application No: | US18380054 |
| Title: | Sustained release formulations of dysoxylum binefacterum | ||
| Publication Date: | 08-02-2024 | File Date: | 13-10-2023 |
| Inventor(s): | Bharate Sonali Sandip; Kumar Vikas; Gupta Mehak; Ghandhi Sumit; Kumar Ajay; Bharate Sandip Bibishan; Vishwakarma Ram | ||
| IPC Classification: | A61K9/16, A61K36/58 | ||
| Abstract: | The present invention relates to the novel formulation for sustained or delayed release of rohitukine-rich Dysoxylum binectariferum extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract/fraction of rohitukine-rich Dysoxylum binectariferum with polymers has resulted in a sustained release of the extract or fraction over a period of 16-24 hrs. The said formulations are useful in the treatment of inflammatory diseases. | ||