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Publication No: US2024041772 [USA] Application No: US18380054
Title: Sustained release formulations of dysoxylum binefacterum
Publication Date: 08-02-2024 File Date: 13-10-2023
Inventor(s): Bharate Sonali Sandip; Kumar Vikas; Gupta Mehak; Ghandhi Sumit; Kumar Ajay; Bharate Sandip Bibishan; Vishwakarma Ram
IPC Classification: A61K9/16, A61K36/58
Abstract: The present invention relates to the novel formulation for sustained or delayed release of rohitukine-rich Dysoxylum binectariferum extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract/fraction of rohitukine-rich Dysoxylum binectariferum with polymers has resulted in a sustained release of the extract or fraction over a period of 16-24 hrs. The said formulations are useful in the treatment of inflammatory diseases.
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Industrial Applications Chemistry, Chemical Processes Polymers [Chemistry, Chemical Processes] Formulations [Drugs and Pharmaceuticals] Nutraceuticals [Drugs and Pharmaceuticals] Process [Environmental (Clean Tech)]