CSIR Technology Portal
CSIR Technology Portal

 Technology Profile

Title:

 tFOCUS System for Produce Water Soluble Nano-Drug

Value Proposition:

Temperature and Flow Control Ultrasonic Spray (tFOCUS) System to make poorly water-soluble therapeutic substances (drugs) to soluble by formulation of these substances into nano size particles, in pure form without any chemical modification the active constituents of substances or use of prohibitive substance. The tFOCUS system has flexibility to vary the process parameters by select the pre-program mode options. 

Summary Application:

The enrichment in bioavailability of the drugs is one of the most important concerning aspects of the pharmaceutical industries. The tFOCUS  System  Enhance the bioavailability of the drug by make these drug into nano-size with narrow particle size distribution which helps amount of drug (dosage level) required to be incorporated to nanocarriers is much less than required when compared to conventionally encapsulated in a tablet form. This is very useful when using expensive phytomolecules or API. Optimal use of phytomolecules/API improves the cost-effectiveness of the drug and reduce the side effects of the drug.

Advantages:

Benchtop system; Green and nonhazardous process to make water soluble drug at low temperature;  Rapid reaction rates and controllable reaction conditions provide energy saving and to achieve nano-drug particulate with a uniform shape and narrow size-distribution respectively.

Tech. Readiness Level:
CSIR-Central Scientific Instruments Organisation
CSIR-Central Scientific Instruments Organisation[CSIR-CSIO]
:  director[at]csio[dot]res[dot]in
:91-172-2657267
:https://www.csio.res.in/
Industrial Applications: Computatuonal Drug Discovery [Drugs and Pharmaceuticals] Food Flavouring [Food, Beverages, Tobacco] Food Processes [Food, Beverages, Tobacco] Formulations [Drugs and Pharmaceuticals] Nutraceuticals [Drugs and Pharmaceuticals] Nutrition [Food, Beverages, Tobacco]
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