CSIR Technology Portal
CSIR Technology Portal

 Technology Profile

Title:

Typhoid Test Kit

Value Proposition:

The kit addresses the need of the hour to develop a fast, rapid and sensitive  immunoassay to detect the Salmonella.

Summary Application:

Typhoid  is a life threatening infection  caused by the Salmonella enterica serovar Typhi and currently emerging  as a major public health problem in developing countries. Diagnosis of Salmonella Typhi  is quite challenging because the symptoms of typhoid fever overlap with a wide range of other diseases. The conventional  methods which include the blood culture and antibody based detection are considered as a gold standard for the diagnostic of typhoid fever. These methods often give rise to false negative results because of the prior intake of antibiotics and hence underestimates the actual occurrence of disease. 

Advantages:

Therefore the need of an hour is to develop a fast, rapid and sensitive  immunoassay  to detect the Salmonella. By considering all these point our  technology focuses on the invention of hand-held opticall system by employing three highly selective biomarkers CdtB, Vi and PagC  specific to S. Typhi  for the detection of typhoidalsalmenollosis. The test would be more  specific and accurate   by providing serological detection of antibodies (IgG/IgM ) against these three biomarkers in typhoid infected patients. Thus the current technology can be useto  provide a rapid, sensitive and reliable immunoassay platform for  detection of  typhoid fever. 

Tech. Readiness Level:
CSIR-Institute of Microbial Technology
CSIR-Institute of Microbial Technology[CSIR-IMTECH]
:  director[at]imtech[dot]res[dot]in
:91-172-2690550
:https://www.imtech.res.in
Industrial Applications: Biotechnology [Biological Science]
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