Continuous and Green (Solvent-free) Process for the Manufacturing of Metformin Hydrochloride (an anti-diabetic drug)

• Continuous process
• Shorter reaction time
• Single-step process
• Colourless product
• Green process: No use of organic solvent
• Cost-effective process: Solvent-free, no product purification step
• Smaller footprint
• Complete conversion of reactants
• Product quality complies with FDA regulatory criteria and standards.

• Anti-diabetic drug for Type II Diabetes
• For women with Polycystic Ovary Syndrome

• Solvent-free, additive-free, and greener production technology
• Single-step reaction with continuous mode by use of a screw reactor
• Low reaction time (5 to 10 min) as compared to the existing process
• High-purity product with less downstreaming process (>95%)
• Easier scale-up to industrial production.