CSIR Technology Portal
CSIR Technology Portal

 Technology Profile

Title:

Phytopharmaceutical Lead for the Management of Mild Cognitive Impairment (MCI) Including Alzheimer's disease

Value Proposition:

Crocus sativus based phytopharmaceutical product for the management of Mild Cognitive Impairment (MCI) including Alzheimer's disease (AD). It contains 20% of total crocins. It Induced Aβ-BEI (clearance across the BBB) and induced the expression of BBB-Aβ clearance proteins. It Showed anti-dementia properties, by significant improvement in STZ induced memory deficit in Morris Water Maze test in rats
It also improved memory, learning in Rat models, while showing Good Safety Profile .

Summary Application:

To be employed for the management of MCI including Alzheimer's disease.

Advantages:

Novel Phytopharmaceutical Formulation for the management of the MCI including Alzheimer disease.

Tech. Readiness Level:
CSIR-Indian Institute of Integrative Medicine
CSIR-Indian Institute of Integrative Medicine[CSIR-IIIM]
:  director[at]iiim[dot]res[dot]in
:91-191-2585222
:https://iiim.res.in
Industrial Applications: Formulations [Drugs and Pharmaceuticals]
Patent(s): US12023365