PsoriaCIM: Non-steroidal, Lavender Oil-based Herbal Cream for Psoriasis Management

A scientifically validated, steroid-free topical formulation offering clinically comparable efficacy to conventional corticosteroid treatments for psoriasis, without associated side effects. Targets the 2-3% global population affected by psoriasis, including 0.44-2.8% in India, with a safe, plant-derived therapeutic alternative

Topical cream formulation containing novel combination of two phytomolecules from lavender oil (Lavandula angustifolia) for management of psoriasis-like skin inflammation. Effective at 2% concentration in cream base against imiquimod-induced psoriasis in preclinical models. Alleviates PASI (Psoriasis Area and Severity Index) scores and reduces psoriasis-specific cytokines (IL-17, IL-23, TNF-α) along with common inflammatory mediators

• Non-steroidal: Avoids corticosteroid-related side effects (skin atrophy, telangiectasia, hypothalamic-pituitary-adrenal suppression)
• Pre-clinically validated: Demonstrated efficacy equivalent to 0.1% mometasone (standard steroid) in preclinical studies
• Dual-action: Combines anti-psoriatic phytomolecules with emollient cream base for enhanced skin barrier repair
• Safety profile: Non-toxic to skin and mucous membranes; suitable for long-term use
• Mechanistic action: Modulates Th17/IL-23 inflammatory pathway central to psoriasis pathogenesis