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 Technology Profile

Title:

Integrated Continuous Flow Process for Daclatasvir Free Base Synthesis
Value Proposition:
  • Fully integrated continuous flow process
  • Time reduced from 12 days to 28.2 minutes
  • Scalable: current yield 11.8 g/day with existing setup
Summary Application:

Integrated flow chemistry route for synthesizing the Hepatitis C drug Daclatasvir.

Significantly reduce process time.
Advantages:

Treatment of Hepatitis C Virus infections
Tech. Readiness Level:
CSIR-Indian Institute of Chemical Technology
CSIR-Indian Institute of Chemical Technology[CSIR-IICT]
:  director[at]iict[dot]res[dot]in
:91-40-27193030
:https://www.iict.res.in
Industrial Applications: Chemistry, Chemical Processes Polymers [Chemistry, Chemical Processes] Formulations [Drugs and Pharmaceuticals]
Patent(s): IN478544 IN558276 US11344858
Photograph(s)